This year Doctor Raymond Boissy and Dr. James J. Nordlund both here in Cincinnati published a paper entitled “Vitiligo: current medical and scientific understanding.” It was published in the Giornale Italiano di Dermatologia E Venereologia in February of this year.
Vitiligo is a relatively common acquired skin depigmentary disease with a complex presentation, therapy, and etiology. Both the prognosis and therapeutic response for patients with vitiligo is unpredictable. Multiple current therapies exist however the efficacy of these are not optimal. The cause of vitiligo appears to be a combination of genetic effects in both the immune system and the melanocyte itself with a precipitating factor instigating their interaction and resulting in the melanocyte destruction. Headway is being made in understanding the etiology of vitiligo that should culminate in new and improved therapies.
The entire paper can be seen at http://www.uvbnarrowband.com/wp-content/uploads/pdfs/2011-Boissy-Nordlund-G-Ital-Dermatol-Venereol.pdf